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Study questions safety of GM corn as France seeks EU ban

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Published 24 February 2012, updated 15 April 2013

Insecticides present in one of Europe’s most controversial genetically modified crops, MON810 maize, may be harmful to humans, French and German researchers say in a new study that could pour fuel over calls asking to limit such plants in the EU.

The study comes as France’s environment and agricultural ministers this week urged the European Commission to seek an EU-wide ban on the cultivation of MON810, EurActiv.fr reported. The maize is outlawed in Austria, Germany, Greece, Hungary and Luxembourg, while France is threatening to re-impose its own ban that was struck down in court if the EU does not act.

Christoph Then, who heads the Testbiotech research firm in Munich, said there is evidence that MON810 produces a toxin that can be harmful to humans through soil, water or animal feed contamination.

The Testbiotech’s study, in conjunction with research done at the University of Caen, shows that insecticides present in genetically engineered maize and similar crops pose a potential risk to humans. The study was released on 17 February.

Although the results are not conclusive and are based on review of high concentrations of toxins, the German-French team of researchers said the finding was a “surprising outcome and this risk was somehow overlooked” in past assessments of biotech crops.

“We don’t know yet the final impact for the human consumer is, it’s too early to say that,” Then said in a telephone interview. “We are very cautious about saying we have proof that the consumer risk is high, that it needs more assessments.”

Monsanto last month announced it would scrap plans to sell the maize in France despite a French court ruling in November that overturned a 2008 government ban on the sale of MON810.

'Safe as its conventional counterpart'

The US-based seed and herbicide company has long maintained that MON810 and other genetically modified crops are safe and more environmentally friendly because they produce higher yields, require fewer pesticides and need less water than conventional seeds.

The European Food Safety Authority in 2009 issued an assessment showing that “maize MON810 is as safe as its conventional counterpart with respect to potential effects on human and animal health” and is unlikely to have “any adverse effect on the environment.” A 2004 study by the Parma, Italy-based EU agency reached similar conclusions.

However, the accuracy of EFSA reports on GM crops have been criticised by MEPs, national governments and researchers – including Then’s Testbiotech – for allegedly relying too heavily on industry-based information and research.

Acknowledging that there are divergent views on GM safety, Then called for additional independent research on the use of the Bacillus thuringiensis, or Bt, toxin that is used in GM crops like MON810 to strengthen their resistance to insects.

Positions: 

“Twenty-fives years of research by independent and public scientists have shown these products to be as safe or safer than conventional counterparts,” Carel du Marchie Sarvaas, director of Green Biotechnology Europe for the EuropaBio industry group, told EurActiv.

Food & Water Europe welcomed the French government’s call for the European Commission to ban MON810. “GM is an outdated technology, and it is draining research time and money away from more promising technologies. We encourage other EU member states to support the French in their bid to stop the GM experiment in Europe,” the organisation's director, Wenonah Hauter, said in a statement.

EurActiv.com

COMMENTS

  • This "study" by green activists was done in a highly artificial context. It is totally irrelevant to real food consumption.

    We have recently published 2 articles which compile numerous publication by independent public research laboratories:
    http://www.marcel-kuntz-ogm.fr/article-no-long-term-effect-92354920.html
    They confirm the food safety of GM derived food.

    Marcel Kuntz, Director of research at CNRS

    By :
    Marcel Kuntz
    - Posted on :
    27/02/2012
  • Perhaps Seralini et al are unaware of:

    ENV/JM/MONO(2007)14
    Organisation de Coopération et de Développement Economiques
    Organisation for Economic Co-operation and Development 19-Jul-2007
    English - Or. English
    ENVIRONMENT DIRECTORATE
    JOINT MEETING OF THE CHEMICALS COMMITTEE AND
    THE WORKING PARTY ON CHEMICALS, PESTICIDES AND BIOTECHNOLOGY
    CONSENSUS DOCUMENT ON SAFETY INFORMATION ON TRANSGENIC PLANTS EXPRESSING
    BACILLUS THURINGIENSIS - DERIVED INSECT CONTROL PROTEINS

    If they look at the page 33 on human risk assessment they will read:

    4. Human Risk Assessment
    65. The acute oral toxicity data on Cry1Ab, Cry1Ac, Cry9C, Cry3A, Cry1F, Cry2Ab2, Cry3Bb1,
    Cry34Ab1, and Cry35Ab1 supports the prediction that the Cry proteins would be non-toxic to humans.
    When proteins are toxic, they are known to act via acute mechanisms and at very low dose level (Sjoblad
    et al., 1992). Therefore, since no effects were seen in the acute tests, even at relatively high dose levels,these δ-endotoxin proteins are not considered toxic to humans. Both the long history of safe use of B.thuringiensis and the acute oral toxicity data allow for a conclusion that these and other δ-endotoxins pose
    negligible toxicity risk to humans. The one aspect of human health concern identified in their assessments
    was the potential for the Cry9C protein to be a food allergen. Cry9C was conditionally registered in the
    U.S. for animal feed uses only, with restrictions on cultivation to provide containment. However some
    unintentional mixing occurred probably either in the field through pollination or after harvest at grain
    handling facilities and resulted in low levels of the toxin appearing in a few processed maize products. The
    registration was subsequently withdrawn at the company‘s request. Studies by the U.S. Food and Drug
    Administration and the Centers for Disease Control and Prevention did not reveal any cases of human
    allergenicity attributable to exposure to Cry9C. One individual who showed possible allergenicity to the
    Cry9C protein by self-administered oral doses and one skin test volunteered for a fully controlled, doubleblind,
    test in a medical centre which proved that he was not allergic to Cry9C protein (Sutton et al., 2003).
    The overall safety record for Bt has been established in laboratory and field studies, which have looked at both formulated Bt sprays and specific Bt genes in planta (Betz et al., 2000; Siegel, 2001; Federici, 2002).

    By :
    Robert Wager
    - Posted on :
    27/02/2012
  • an answer by Henry Miller:

    http://www.forbes.com/sites/henrymiller/2012/02/22/the-science-of-things-that-arent-so/

    By :
    anonymous
    - Posted on :
    27/02/2012
  • What is being missed is the fact that these crops are cauing damage to the natural flora.

    By :
    Victoria
    - Posted on :
    08/03/2012
Ready for harvest. Monsanto photo
Background: 

EU countries are able to restrict genetically modified crop cultivation under strict conditions as authorisation licences are valid across the 27-country bloc, in accordance with the principles of the EU's single market.

Several member states have repeatedly invoked an EU safeguard clause enabling them to suspend the marketing or growth on their territory of GM crops that enjoy EU-wide authorisation, but the European Commission has never substantiated their applications and has always ordered the lifting of national bans.

In addition, the safety assessments performed by the European Food Safety Authority have come under criticism over the years. The EU executive has tried to introduce practical changes to the EFSA's GMO-approval process and in spring 2008, it mandated  the agency to revise its guidance for the long-term environmental risk assessment of GM plants.

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